Inverted Repeats in Viral Genomes
نویسندگان
چکیده
We investigate 738 complete genomes of viruses to detect the presence of short inverted repeats. The number of inverted repeats found is compared with the prediction obtained for a Bernoullian and for a Markovian control model. We find as a statistical regularity that the number of observed inverted repeats is often greater than the one expected in terms of a Bernoullian or Markovian model in several of the viruses and in almost all those with a genome longer than 30,000 bp.
منابع مشابه
Comparative genomics study of inverted repeats in bacteria
MOTIVATION Comparative genomics provides a powerful way to investigate regularities and differences observed at DNA level across species. Here we study the number and location of inverted repeats occurring in complete genomes of bacteria. Inverted repeats are compatible with the formation of hairpin structures in the messenger RNA. Some of these structures are known to be rho-independent intrin...
متن کاملAssociations between inverted repeats and the structural evolution of bacterial genomes.
The stability of the structure of bacterial genomes is challenged by recombination events. Since major rearrangements (i.e., inversions) are thought to frequently operate by homologous recombination between inverted repeats, we analyzed the presence and distribution of such repeats in bacterial genomes and their relation to the conservation of chromosomal structure. First, we show that there is...
متن کاملA Genome-wide Analysis of Perfect Inverted Repeats in Arabidopsis Thaliana
A GENOME-WIDE ANALYSIS OF PERFECT INVERTED REPEATS IN ARABIDOPSIS THALIANA by Sutharzan Sreeskandarajan Perfect inverted repeats play wide variety of roles in genomes. In this study, we conduct a genome-wide analysis of perfect inverted repeats in Arabidopsis thaliana and explore the biological significance of the observed inverted repeat distribution. The roles of palindromic sequences are rev...
متن کاملDetection of template strand switching during initiation and termination of DNA replication of porcine circovirus.
Nucleotide substitution mutagenesis was conducted to investigate the importance of the inverted repeats (palindrome) at the origin of DNA replication (Ori) of porcine circovirus type 1 (PCV1). Viral genomes with engineered mutations on either arm or both arms of the palindrome were not impaired in protein synthesis and yielded infectious progeny viruses with restored or new palindromes. Thus, a...
متن کاملEvidence for Active Maintenance of Inverted Repeat Structures Identified by a Comparative Genomic Approach
Inverted repeats have been found to occur in both prokaryotic and eukaryotic genomes. Usually they are short and some have important functions in various biological processes. However, long inverted repeats are rare and can cause genome instability. Analyses of C. elegans genome identified long, nearly-perfect inverted repeat sequences involving both divergently and convergently oriented homolo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2004